2021 Indianapolis Colts Roster
| Jersey | POS | Height | Weight | Exp | Age | College | High School | Rating |
|---|---|---|---|---|---|---|---|---|
| 49 | OLB | 6-0 | 229 | 4 | 26 | Houston | Hightower | |
| 41 | SS | 5-10 | 195 | 9 | 32 | Central Michigan | Riverview | |
| 81 | TE | 6-5 | 267 | 4 | 28 | Virginia Commonwealth | ||
| 6 | K | 5-10 | 183 | 4 | 26 | Miami (FL) | Summit | |
| 52 | DE | 6-4 | 250 | 3 | 26 | TCU | Prosper | |
| 99 | DT | 6-7 | 295 | 6 | 27 | Oregon | Punahou | |
| 1 | WR | 6-1 | 208 | 3 | 24 | Ohio State | St. Vincent-St. Mary | |
| 38 | DB | 6-0 | 208 | 8 | 31 | Ohio | De La Salle | |
| 73 | OT | 6-7 | 315 | 5 | 27 | Bucknell | Paulsboro | |
| 84 | TE | 6-6 | 262 | 9 | 31 | Western Kentucky | Cathedral | |
| 16 | WR | 6-2 | 215 | 3 | 24 | Malone College | Reynoldsburg | |
| 4 | QB | 6-1 | 222 | 0 | 23 | Texas | Westlake | |
| 79 | OT | 6-7 | 312 | 9 | 31 | Central Michigan | Stoney Creek | |
| 44 | OLB | 6-0 | 235 | 4 | 25 | Syracuse | La Salle College | |
| 75 | OG | 6-6 | 305 | 0 | 23 | Penn State | Cranford Sr | |
| 59 | LB | 6-0 | 225 | 2 | 25 | Michigan | Marmion Academy | |
| 64 | OG | 6-4 | 310 | 7 | 29 | West Virginia | ||
| 83 | TE | 6-3 | 242 | 0 | 23 | SMU | Westlake | |
| 13 | WR | 5-10 | 183 | 10 | 32 | Florida International | Miami Springs Senior | |
| 21 | RB | 5-9 | 196 | 4 | 25 | NC State | Garner | |
| 35 | RB | 6-0 | 218 | 0 | 22 | Duke | Pace Academy | |
| 78 | C | 6-4 | 307 | 6 | 28 | Alabama | Lakota West | |
| 53 | OLB | 6-2 | 230 | 4 | 26 | South Carolina State | Lake View | |
| 25 | RB | 6-0 | 212 | 5 | 25 | South Florida | Booker | |
| 23 | CB | 5-9 | 190 | 5 | 26 | Valdosta State | ||
| 97 | DE | 6-4 | 250 | 5 | 26 | Miami (FL) | Don Bosco Prep | |
| 56 | OG | 6-5 | 330 | 4 | 25 | Notre Dame | Red Bank Catholic | |
| 54 | DE | 6-6 | 276 | 0 | 22 | Vanderbilt | Ranchview | |
| 30 | SS | 6-1 | 202 | 4 | 28 | Central Arkansas | ||
| 58 | MLB | 6-2 | 235 | 3 | 25 | Stanford | Foothill | |
| 14 | WR | 6-2 | 214 | 4 | 27 | Old Dominion | Dr. Henry Wise | |
| 10 | WR | 6-4 | 225 | 2 | 23 | Washington State | Henry | |
| 51 | DE | 6-3 | 265 | 0 | 23 | Michigan | Bishop Hendricken | |
| 63 | C | 6-4 | 301 | 2 | 25 | Ball State | Adams | |
| 11 | WR | 6-4 | 223 | 2 | 24 | USC | Oaks Christian | |
| 69 | OT | 6-7 | 332 | 4 | 27 | TCU | Lakewood | |
| 62 | OG | 6-3 | 314 | 6 | 29 | Minnesota State | ||
| 46 | LS | 6-2 | 238 | 5 | 29 | William & Mary | ||
| 27 | CB | 6-1 | 210 | 9 | 31 | Florida State | Norland | |
| 91 | DE | 6-4 | 260 | 4 | 26 | Notre Dame | Eagles Landing Christian Academy | |
| 34 | CB | 5-10 | 176 | 2 | 24 | Massachusetts | Blake | |
| 8 | P | 6-0 | 195 | 5 | 27 | Hawaii | ||
| 0 | N/A | 6-1 | 210 | 11 | 34 | Rice | Smithson Valley | |
| 72 | OT | 6-6 | 312 | 4 | 25 | Auburn | Olathe South | |
| 45 | LB | 6-4 | 227 | 3 | 26 | Tarleton State | North Crowley | |
| 95 | DT | 6-2 | 293 | 3 | 26 | South Carolina | Murphy | |
| 90 | DT | 6-4 | 315 | 5 | 28 | Albany State (Ga.) | Mitchell County | |
| 17 | WR | 6-5 | 225 | 0 | 24 | Charleston | ||
| 28 | RB | 5-10 | 226 | 2 | 23 | Wisconsin | Salem | |
| 57 | DE | 6-5 | 252 | 4 | 26 | Rutgers | Barringer | |
| 2 | QB | 6-5 | 240 | 6 | 29 | North Dakota State | Century | |
| 37 | SS | 5-11 | 215 | 3 | 25 | Michigan State | Lumen Christi | |
| 26 | CB | 6-0 | 190 | 3 | 25 | Temple | Southwest DeKalb |